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Laboratory of Polymers & Biomaterials

Institute of Fundamental Technological Research

  • 1 Oliwia Jeznach as a laureate of the Kosciuszko Foundation scholarship

    It is our pleasure to inform you that our team member, Mrs. Oliwia Jeznach has become one of the laureate of scholarship granted by the Kosciuszko Foundation. Congratulations Oliwia!
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  • 2 Professor dr hab. Andrzej Ziabicki

    We announce with very deep regret that on March 14th, 2019 left us our great Master and Teacher - Professor dr hab. Andrzej Ziabicki.
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  • 3 New internschip students in our laboratory!

    As every year new internship students will join our research team! To get know who will join us this summer please see in the link below...
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  • 4 Polish-Israeli Conference on Electrospinning and Tissue Engineering

    It is our great pleasure to announce the 1st Polish-Israeli Conference on Electrospinning and Tissue Engineering (PICETE 2018), which will be held on 4-5th October 2018 in Warsaw, Poland, at the Institute of Fundamental Technological Research, Polish Academy of Sciences.Kindly visit the PICETE2018 conference website.
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  • 5 New OPUS and PRELUDIUM grant in our laboratory!

    We would like to inform that National Centre of Science granted the project of our laboratory leader, prof. Paweł Sajkiewicz and our colleague, Piotr Denis, M.Sc., in OPUS and PRELUDIUM program, respectively. Both, projects were subbmited in the ST8 category - Process and production engineering. Congratulations for the project leaders!
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Source of founding: National Science Centre, SONATA Program, V edition

Duration: March 2014- March 2017 

Project No.:  2013/09/D/ST8/04009

Project menager/ principal investigator:  Dorota Kołbuk, Ph.D

Participants: Piotr Denis, M.Sc., Monika Bill, Maryla Moczulska

Aims

The aim of proposed research is to investigate polymers substrate supermolecular structure effect, mainly crystallinity, on the cells' activity and proliferation during in-vitro studies. The specific goal of the project is analysis of the degree of crystallinity in one- and two-componet polymers\foils in terms of cellular response. Determination of the mechanisms deciding about the increase of bioactivity of the material with an addition of gelatin is a supplementary aim.

Abstract

The research project concerns the matter of polymer crystallinity influence on cells morphology, activity and proliferation. Commonly used methods forming three-dimensional scaffolds do not take into account crystallinity optimisation. It is therefore very important to know the influence of different crystallinity on cells response, without changing others parameters. To achieve this, it is necessary to analyse more in detail substrate based on one- and two-component foils, formed from the melt and solution. Degree of crystallinity differentiation is possible as an effect of investigation of fundamental relationship between molecular weight of polymer, speed of cooling (formation from melt); type of solvent and amount of biopolymer (formation from solutions).

Significance of the project for science/ Motivation

 It is expected that an appropriate forming methodology render the optimal properties of one- and two-componet foils for efficient growth, activity and cells proliferation during the in-vitro study. It is anticipated that the proposed and implemented research will expand scientific knowledge about the crystallinity effect on the cell substrates functionality and contribute to the more complete literature description of the efficient degree of crystallinity control of the substrates formed by the other methods.

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